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Microarray

We run a full Affymetrix microarray service line for whole-genome profiling, including:

  • Gene expression
  • miRNA
  • Copy number
  • Single nucleotide polymorphisms

SAMPLE TYPES
Microarray methods are validated in-house for the following sample types:

  • Cell pellets
  • Frozen tissue
  • Formalin-fixed paraffin embedded (FFPE) tissue
  • Whole blood

Please contact us for sample collection and processing SOPs, to ensure that your precious tissue is best maintained for microarray analysis.

DATA ANALYSIS

We have a full bioinformatics and biostatistics staff to aid in study design and data analysis. Each microarray study has different objectives, and we encourage discussion with our data analysis group before the study is underway to ensure that the study design will meet the data analysis objectives.

We report data back to the customer in a variety of custom formats, often including:

  • Study Design
  • Data QC
  • Data Preparation
    • Data transformation
    • Normalization
    • % tumor correction
  • Idenitification of Differentially Expresed Genes (DEGs)
    • t-test
    • ANOVA
  • Group/subclass analysis
    • Clustering (supervised & unsupervised)
    • Heatmap
    • Principle Components Analysis
  • Ontology
  • Pathway analysis